Cerebrovascular and blood-brain barrier impairments in Huntington’s disease: potential implications for its pathophysiology
Publication: Annals of Neurology, 2015
Quantitative Ultrasound Spectroscopic Imaging for Characterization of Disease Extent in Prostate Cancer Patients
Publication: Translational Oncology, 2015
Non-invasive evaluation of breast cancer response to chemotherapy using quantitative ultrasonic backscatter parameters
Publication: Medical Imaging Analysis, 2015
Prostate clinical study of a full inversion unconstrained ultrasound elastography technique
Publication: SPIE Medical Imaging, 2014
Immune correlates of HIV exposure without infection in foreskins of men from Rakai, Uganda
Publication: Mucosal Immunology, 2014
Go Large! Opportunities and Challenges Presented by Whole-Mount Histopathology
Publication: Pathology Informatics, 2014
Targeting the Renin–Angiotensin System Combined With an Antioxidant Is Highly Effective in Mitigating Radiation-Induced Lung Damage
Publication: International Journal of Radiation Oncology, 2014
Early prediction of therapy responses and outcomes in breast cancer patients using quantitative ultrasound spectral texture
Publication: Oncotarget, 2014
HIV Infection in Uncircumcised Men Is Associated With Altered CD8 T-Cell Function But Normal CD4 T-cell Numbers in the Foreskin
Publication: Journal of Infectious Diseases, 2014
Biomechanical Modeling and Inverse Problem Based Elasticity Imaging for Prostate Cancer Diagnosis
Publication: PhD thesis, Western
A Texture Based Approach to Automated Detection of Diagnostically Relevant Regions in Breast Digital Pathology
Publication: MICCAI, Workshop on Breast Image Analysis, 2013
Irinotecan Sucrosofate Liposome Injection, MM-398, Demonstrates Superior Activity and Control of Hypoxia as Measured through Longitudinal Imaging Using [18F]FAZA PET Compared to Free Irinotecan in a Colon Adenocarcinoma Xenograft Model
Publication: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2013
Hypoxic activation of the PERK/eIF2a arm of the unfolded protein response promotes metastasis through induction of LAMP3
Publication: Clinical Cancer Research, 2013
Quantification of Fibrosis in Infarcted Swine Hearts by ex vivo Late Gadolinium Enhancement and Diffusion-Weighted MRI Methods
Publication: Physics in Medicine and Biology, 2013
3D Co-registration of MRI and Histology in a Mouse Model of Obesity
Publication: ImNO – Pre-Clinical Imaging, 2013
Development of a Multi-Modality Imaging Pipeline for the Interrogation of Phenotypic Differences in the Tumor Microenvironment of Patient-Derived Colon Cancer Xenografts
Publication: ImNO – Adaptive Interventions in Radiation Oncology, 2013
Quantitative Ultrasound Evaluation of Tumour Cell Death Response in Locally Advanced Breast Cancer Patients Receiving Chemotherapy
Publication: Clinical Cancer Research, 2013
Evaluation of Neoadjuvant Chemotherapy Response in Women with Locally Advanced Breast Cancer Using Ultrasound Elastography
Publication: Translational Oncology, 2013
Development and Proof-of-Concept of Three-Dimensional Lung Histology Volumes
Publication: Medical Imaging: Biomedical Applications in Molecular, Structural, and Functional Imaging, 2012
Sequence Dependence of MEK Inhibitor AZD6244 Combined with Gemcitabine for Treatment of Biliary Cancer
Publication: Clinical Cancer Research, 2012
Diffuse Optical Imaging for Monitoring Treatment Response in Breast Cancer Patients
Publication: IEEE Engineering in Medicine and Biology, 2012
WFDC1/ps20: A Host Factor that Influences the Neutrophil Response to Murine Hepatitis Virus (MHV) 1 Infection
Publication: Antiviral Research, 2012
3D Pathology Volumetric Technique: A Method for Calculating Breast Tumour Volume from Whole-Mount Serial Section Images
Publication: International Journal of Breast Cancer, 2012
Diffuse Optical Spectroscopy Evaluation of Treatment Response in Women with Locally Advanced Breast Cancer Receiving Neoadjuvant Chemotherapy
Publication: Translational Oncology, 2012
Targeting Tumour Metabolism through HIF-1 Inhibition Enhances Radiation Response in Cervix and Head and Neck Xenograft Tumours
Publication:MSc Thesis, 2011
Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis
Publication: American Journal of Transplantation, 2011
Increasing specimen coverage using digital whole-mount breast pathology: Implementation, clinical feasibility and application in research
Publication: Computerized Medical Imaging and Graphics, 2011
Biomechanical Property Quantification of Prostate Cancer by Quasi-static MR Elastography at 7 Telsa of Radical Prostatectomy, and Correlation with Whole Mount Histology
Publication: The International Society for Magnetic Resonance in Medicine, 2011
Megapixel Digital PCR
Publication: Nature Methods, 2011
Evaluation of Microscopic Disease in Oral Tongue Cancer Using Whole-Mount Histopathologic Techniques: Implications for the Management of Head-and-Neck Cancers
Publication: International Journal of Radiation Oncology * Biology * Physics, 2011
Hypoxia predicts aggressive growth and spontaneous metastasis formation from orthotopically-grown primary xenografts of human pancreatic cancer
Publication: Cancer Research, 2011
Evaluating the Extent of Cell Death in 3D High Frequency Ultrasound by Registration with Whole Mount-tumor Histopathology
Publication: Medical Physics, 2010
Registration of In Vivo Prostate Magnetic Resonance Images to Digital Histopathology Images
Publication: Prostate Cancer Imaging, Computer-Aided Diagnosis, Prognosis and Intervention/ Lecture Notes in Computer Science/ Robarts Research Institute/ University of Western Ontario, 2010
Technical Note: Fiducial Markers for Correlation of Whole-Specimen Histopathology with MR Imaging at 7 Tesla
Publication: Medical Physics, 2010
Activation of Src and Src-associated Signaling Pathways in Relation to Hypoxia in Human Cancer Zenograft Models
Publication: International Journal of Cancer, 2008
Developing a Methodology for Three-Dimensional Correlation of PET-CT images and Whole-Mount Histopathology in Non-Small-Cell Lung Cancer
Publication: Current Oncology, 2008
Effect of Distributional Heterogeneity on the Analysis of Tumor Hypoxia Based Carbonic Anhydrase IX
Publication: Laboratory Investigation, 2007
Imaging and Modulating Antisense Microdistribution in Solid Human Xenograft Tumor Models
Publication: Clinical Cancer Research, 2007
Measurements of Aneurysm Morphology Determined by 3-D Micro-Ultrasound Imaging as Potential Quantitative Biomarkers in a Mouse Aneurysm Model
Publication: Ultrasound in Medicine & Biology, 2007
Measurement of Signaling Pathway Activities in Solid Tumor Fine-needle Biopsies by Slide-based Cytometry
Publication: Diagnostic Molecular Pathology, 2007
Predictive and Pharmacodynamic Biomarker Studies in Tumor and Skin Tissue Samples of Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Erlotinib
Publication: Journal of Clinical Oncology, 2007
Acquiring Multiple Images of Large Tissue Sections in Both Fluorescence and Transmitted Light using the Laser Scanning Confocal TISSUEscope
XXXIII International Congress of the International Society for Analytical Cytology, 2006
Multiplexed and quantitative study of biomarker expression in tumor specimens using quantum dots
Publication: SPIE – Colloidal Quantum Dots for Biomedical Applications, 2006
A Phase 2 Clinical and Pharmacodynamic Study of Temsirolimus in Advanced Neuroendocrine Carcinomas
Publication: British Journal of Cancer, 2006
A New Wide Field-of-view Confocal Imaging System and its Applications in Drug Discovery and Pathology
Publication: Optical Methods in Drug Discovery and Development, 2005
A Phase 2 Trial with Pharmacodynamic Endpoints of the Proteasome Inhibitor Bortezomib in Patients with Metastatic Colorectal Cancer
Publication: Clinical Cancer Research, 2005
Hyperspectral Unmixing for Removing Autofluorescence from Paraffin-Embedded, Formalin-fixed Tissue Sections
Publication: SPIE Photonic Applications in Biosensing and Imaging, 2005
A High-resolution MACROscope with Differential Phase Contrast, Transmitted Light, Confocal Fluorescence, and Hyperspectral Capabilities for Large-area Tissue Imaging
Publication: IEEE Selected Topics in Quantum Electronics, 2005
